The Liquid Chromatography -Triple Quadrupole Mass Spectrometer LC-TQ 5000 consists of a high performance liquid chromatography spectrometer and a triple quadrupole mass spectrometer, and is a truly domestic liquid chromatography tandem mass spectrometry system. With more than 30 years of experience in developing and manufacturing mass spectrometers, Hexin Instrument experienced three stages (from technical innovation to breakthroughs in core components to industrialization of the entire instrument) to achieve domestic production of the triple quadrupole mass spectrometer by tackling key problems in three years, realizing domestic production of key components such as the high efficiency ion source, the triple quadrupole mass analyzer and high voltage radio frequency (RF) power supply. Moreover, we have applied for dozens of national invention patents and developed a triple quadrupole mass spectrometer with independent intellectual property rights.